Alexandre obtained a graduated in Computational Physics (1999), a Master's Degree in Physics (2002), and a Ph.D. in Physics (2006) at Instituto de Física de São Carlos (IFSC) from São Paulo University (USP). Developed postdoctoral research in Computational Biophysics at IFSC-USP between 2006 and 2008 and in Biological Physics at Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) from USP between 2008 and 2010. Since 2011 he is an assistant professor at the Department of Physics of Instituto de Biociências Letras e Ciências Exatas (IBILCE) from São Paulo State University (UNESP) in São José do Rio Preto, Brazil, and currently is an affiliated researcher at Istituto Italiano di Tecnologia (IIT) in Genoa.
He has been working in the area of computer simulations, with emphasis on Molecular Dynamics since 2002, when he started his Ph.D. At UNESP he has been working in the area of computer simulations focusing on systems of environmental and biological interest. In the last 5 years, he has been concentrating his research on studies, through computer simulations, of antimicrobial peptides, Dengue virus, receptor ligand-type systems, the development of simulation methods, and the development of models for ligands of pharmacological interest. At IIT, Alexandre is investigating the envelope protein of Dengue virus using computer simulations in a search for molecules that inhibits the virus invasion of the cell and new approachs in the development of a vaccine against the virus.